Wednesday, February 02, 2011

US Patent 7879819 - Nanoparticle drug delivery for diabetes treatment

GP Medical has built a considerable patent portfolio for methods of using nanoparticles for drug delivery such as US Patent 7879313 which also issued this week. This patent includes more specific claims toward using nanoparticles to deliver anti-diabetic drugs. Claim 1 reads:

1. A method of treating diabetes in a subject, comprising

administering bioactive nanoparticles to said subject,

wherein said bioactive nanoparticles consist of a positively charged chitosan, a negatively charged organic compound, and at least one anti-diabetic drug,

wherein a shell portion of said nanoparticles is dominated by said positively charged chitosan, and

wherein a core portion of said nanoparticles is formed by electrostatically complexing the positively charged chitosan and said negatively charged.