Wednesday, July 08, 2009

US Patent 7556826 - Chewable nanoparticle composition for drug delivery

This patent from GP Medical teaches a nanoparticle drug delivery system for oral administration of proteins or peptides and suitable for animal feeding. Claim 1 reads:

1. A chewable composition for feeding an animal subject comprising a filler substance and nanoparticles that are blended with said filler substance, said nanoparticles comprising:

a shell portion that is dominated by positively charged chitosan,

a core portion that contains negatively charged substrate,

wherein said negatively charged substrate is at least partially neutralized with a portion of said positively charged chitosan in the core portion,

wherein said substrate is PGA, and

at least one bioactive agent loaded within said nanoparticles.