US Patent 7531503 - Artificial tissue incorporating bioreleasing nanoparticles
http://www.freepatentsonline.com/7531503.html
Tissue engineering involves the artificial replacement of biostructures such as bone and cartilage. This patent from Wake Forest University Health Sciences teaches a material applicable to tissue engineering incorporating nanoparticles to assist in the delivery of therapeutic compounds provided to counteract adverse immune responses. Claim 1 reads:
1. An electrospun matrix having a three-dimensional ultrastructure of interconnected fibers and pores to permit cell attachment and further comprising at least one nanoparticle incorporated within the matrix, wherein the nanoparticle is coupled to a therapeutic agent and the therapeutic agent is releasable from the nanoparticle by application of radiation.
Tissue engineering involves the artificial replacement of biostructures such as bone and cartilage. This patent from Wake Forest University Health Sciences teaches a material applicable to tissue engineering incorporating nanoparticles to assist in the delivery of therapeutic compounds provided to counteract adverse immune responses. Claim 1 reads:
1. An electrospun matrix having a three-dimensional ultrastructure of interconnected fibers and pores to permit cell attachment and further comprising at least one nanoparticle incorporated within the matrix, wherein the nanoparticle is coupled to a therapeutic agent and the therapeutic agent is releasable from the nanoparticle by application of radiation.
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