Thursday, July 07, 2011

US Patent 7972819 - Disrupting cells and amplifying nucleic acids using gold nanorods

This patent from Samsung teaches how gold nanorods can be used in place of magnetic beads to improve cell lysis to obtain and amplify DNA. Claim 1 reads:

1. A method of continuously disrupting cells and amplifying nucleic acids in a single microchamber comprising:

introducing a solution containing cells and unmodified gold nanorods into a microchamber;

irradiating a laser onto the gold nanorods to disrupt the cells; and

amplifying a nucleic acid from the disrupted cells in the microchamber.