US Patent 7597278 - Method of producing purified medicinal nanoparticle suspensions

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Several methods have been developed to produce nanoparticle suspensions to facilitate the delivery or absorption of drugs. However, these methods can often result in the inclusion of contamination in the suspension. This patent based on research from Osaka University teaches a method capable of improving the purity of such nanoparticle suspensions. Claim 1 reads:

1. A method of producing a medicinal nanoparticle suspension, comprising the steps of:

adding a poorly water-soluble or water-insoluble medicinal ingredient of a drug into a poor solvent to form a suspending solution; and

irradiating the suspending solution with a laser having a wavelength that is absorbed by the medicinal ingredient to grind the medicinal ingredient in the suspending solution to form nanoparticles.