Tuesday, January 11, 2011

US Patent 7867984 - Obesity treatment using nanoparticles


Polymeric nanoparticles have been investigated to facilitate drug delivery for many years. This latest patent from GP Medical teaches using nanoparticle delivery for appetite-suppressing hormones. Claim 1 reads:

1. A method of treating obesity in a subject in need thereof comprising

identifying a subject in need of treatment for obesity and administering bioactive nanoparticles to said subject,

wherein said nanoparticles consist of positively charged chitosan, a negatively charged substrate, and at least one appetite-suppressing agent,

wherein a shell portion of said nanoparticles is dominated by said positively charged chitosan, and

wherein said negatively charged substrate is at least partially neutralized with a portion of said positively charged chitosan in the core portion of said nanoparticles.